Home
Antibodies
Proteins
IVD Raw Materials
Assay Kits
ELISA Kits
KD/KO Validation
About Us
Enzymes

Tau(Phospho-Thr205) Antibody #11108

Review:
Datasheet PDF
add to favorites
Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
Total:
ADD TO CART
 
Datasheet Images Protocol
Description
  • Product NameTau(Phospho-Thr205) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of Tau only when phosphorylated at threonine 205.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 205 (P-G-T(p)-P-G) derived from Human Tau.
  • Target NameTau
  • ModificationPhospho
  • Alternative Names    MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau
  • Accession No. Swiss-Prot: P10636
    NCBI Protein: NP _001116538.1
  • UniprotP10636
  • Gene ID4137;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology. In Prog Neurobiol on 2021 Nov by Maria Rosaria Tropea, Domenica D Li Puma,et al..PMID:34453977, , (2021),
PMID: 34453977
A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies. In Signal Transduct Target Ther on 2021 Jul 14 by Jie Zheng, Na Tian et al..PMID:34262014, , (2021),
PMID: 34262014
Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission. In Cell Stem Cell on 2020 Mar 5 by Jie Zheng, Hong-Lian Li,et al..PMID:31978364, , (2020),
PMID: 31978364
LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1.In J Exp Clin Cancer Res.On 2018 Mar 12 by Chang ZW, Jia YX et al..PMID:29530057, , (2019),
PMID: 29530057
View All Published Papers Troxerutin cerebroprotein hydrolysate injection ameliorates neurovascular injury induced by traumatic brain injury �C via endothelial nitric oxide synthase pathway regulation .In Int J Neurosci. On 2018 Dec by Zhao H, Liu Y et al..PMID:29883225 , , (2018),
PMID: 29883225
The SMAC Mimetic APG-1387 Sensitizes Immune-Mediated Cell Apoptosis in Hepatocellular Carcinoma.In Front Pharmacol. On 2018 Nov 6 by Chen Z, Chen J et al..PMID: 30459627, , (2018),
PMID: 30459627
Melatonin ameliorates Aβ1-42-induced Alzheimer's cognitive deficits in mouse model.In J Pharm Pharmacol.On 2018 Jan by Gong YH, Hua N et al..PMID: 28994117 , , (2018),
PMID: 28994117
Cnga2 Knockout Mice Display Alzheimer's-Like Behavior Abnormities and Pathological Changes .In Mol Neurobiolon 2016 Sep by Ao-Ji Xie, En-Jie Liu et al..PMID: 26377105, , (2016),
PMID: 26377105
Olfactory Deprivation Hastens Alzheimer-Like Pathologies in a Human Tau-Overexpressed Mouse Model via Activation of cdk5.In Mol Neurobiol.On 2016 Jan by Li K, Liu FF et al..PMID:25465240, , (2016),
PMID: 25465240
Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease.In Transl Psychiatry on 2016 Oct 4 by S-S Jiao , L-L Shen et al..PMID:27701410 , , (2016),
PMID: 27701410
Extrasynaptic NMDA Receptor-Induced Tau Overexpression Mediates Neuronal Death Through Suppressing Survival Signaling ERK Phosphorylation.In Cell Death Dis on 2016 Nov 3 by Xu-Ying Sun , Qing-Zhang Tuo et al..PMID: 27809304, , (2016),
PMID: 27809304
Region-specific expression of tau, amyloid-β protein precursor, and synaptic proteins at physiological condition or under endoplasmic reticulum stress in rats.In J Alzheimers Dis on 2014 by Li Lin, Shu-Sheng Yang, et al..PMID: 24787918, , (2014),
PMID: 24787918
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.In J Neurochem on 2012 Jan by Chen LM, Xiong YS,et al..PMID:21496024, , (2012),
PMID: 21496024
Synaptic released zinc promotes tau hyperphosphorylation by inhibition of protein phosphatase 2A (PP2A). In J Biol Chem on 2012 Mar 30 by Xu-Ying Sun, Yu-Ping Wei, et al..PMID: 22334661 , , (2012),
PMID: 22334661
Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats.In Eur J Anaesthesiol on 2010 Sep by Tan W, Cao X, et al..PMID:20485178, , (2010),
PMID: 20485178
Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats.In Eur J Anaesthesiol on 2010 Sep by Tan W, Cao X, et al..PMID:20485178, , (2010),
PMID: 20485178
Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats.In Clin Exp Pharmacol Physiol on 2010 Oct by Tan WF, Cao XZ,et al..PMID:20659131, , (2010),
PMID: 20659131
Please let us know if you have published research using #11108 so that we can cite your reference.

Customer Reviews and Rankings

No comment
Total 0 results, divided into1 pages. First Prev Next Last

My Review

Username:Anonymous user
E-mail:
Ratings:
Content:
Verification code:captcha

Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep