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Enzymes

Myosin Light Chain 2 (Phospho-Ser19) Antibody #11114

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
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Description
  • Product NameMyosin Light Chain 2 (Phospho-Ser19) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Rt
  • SpecificityThe antibody detects endogenous level of Myosin Light Chain 2 only when phosphorylated at serine 19.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 19 (A-T-S(p)-N-V) derived from Human Myosin Light Chain 2.
  • Target NameMyosin Light Chain 2
  • ModificationPhospho
  • Alternative Names    MLC-2a; MLC2a; MLRA; MYL7; MYLC2A
  • Accession No. Swiss-Prot: P19105
    NCBI Protein: NP_006088.2
  • UniprotP19105
  • Gene ID10627;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

FOXD3 confers chemo-sensitivity in ovarian cancer through a miR-335/DAAM1/myosin II axis-dependent mechanismInJ Ovarian ResOn2023 Jan 10byShufen Wang?1,?Yan Ma? et al..PMID:?36627652, , (2023),
PMID: 36627652
Gastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC2 pathway activationIn Pharm BiolOn2023 DecbyZhi Guo , Xuan Yang et al..PMID:37211627, , (2023),
PMID: 37211627
Tetramethylpyrazine Suppresses the Enhanced Ca2+ Sensitivity through Inhibiting the Expression of RhoA-ROCK in Artery of Simulated Weightlessness Rats., , (2022),
PMID: #N/A
Phosphorylated myosin light chain 2 (p-MLC2) as a molecular marker of antemortem coronary artery spasm.In Med Sci Monit on 2016 Sep 19 by Liliang Li, Yuhua Li et al..PMID: 27643564, , (2016),
PMID: 27643564
View All Published Papers TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages.In J Immunol on 2014 May 1 by Yoshikuni Goto, Kenji Ogawa et al..PMID:24688025, , (2014),
PMID: 24688025
Please let us know if you have published research using #11114 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep