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Sunitinib Malate

S0374
Review: comment rank 5 pdf
  Catalog No. Package Size Price
S0374-1 100mg $57.00
S0374-2 200mg $83.00
S0374-3 500mg $101.00

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Description
  • Product Name Sunitinib Malate
  • Brief Description Inhibitors
  • Purification 98.00%
  • Biological Activity Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor. Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models.
  • Target Name FGFR inhibitor; PDGFR inhibitor; VEGFR inhibitor
  • CAS No. 341031-54-7
  • Calculated MW 532.56
  • Formulation C26H33FN4O7
  • Storage 3 years -20˚C powder;2 years -80˚C in solvent;
Images
  • Sunitinib Malate - SAB | Signalway Antibody


Product Description

Research Area:Cancer
SMILES:CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C.C([C@@H](C(=O)O)O)C(=O)O
Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
Receptor:FGFR1; PDGFRβ; VEGFR2
Boling pt:
Melting pt:189-191C
Solubility:DMSO: 15 mg/mL (28.16 mM)
Appearance:Orange Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

Regerences

1. Sun L, et al. J Med Chem, 2003, 46(7), 1116-1119.

    Please let us know if you have published research using #S0374 so that we can cite your reference.
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