• Product NameActin-related protein 2/3 complex subunit 3 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total Actin-related protein 2/3 complex subunit 3 polyclonal antibody.
• Immunogen Typeprotein
• Immunogen DescriptionRecombinant human Actin-related protein 2/3 complex subunit 3 protein
• Target NameActin-related protein 2/3 complex subunit 3
• Alternative Names    ARPC3
• Accession No. Swiss-Prot#: O15145
• UniprotO15145
• Gene ID10094;
• Calculated MW 20kd
• Formulation Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Storage Store at -20˚C

• Western blotting: 1:500 - 1:1000
  

p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

[1] "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins."Machesky L.M., Reeves E., Wientjes F., Mattheyse F.J., Grogan A., Totty N.F., Burlingame A.L., Hsuan J.

• Actin-related protein 2/3 complex subunit 3Antibody at 2ug/ml + 293T whole cell lysate at 20ug SecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilution Predicted band size : 20 kDa Observed band size : 75 kDa

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting