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Recombinant Human Melanoma-associated antigen 1 (MAGEA1)

AP74655
Review: comment rank 5 pdf
  Catalog No. Package Size Price
AP74655-1 10ug $249.00
AP74655-2 20ug $399.00
AP74655-3 50ug $789.00
AP74655-4 100ug $1109.00

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Description
  • Product Name Recombinant Human Melanoma-associated antigen 1 (MAGEA1)
  • Brief Description Recombinant Human Melanoma-associated antigen 1 (MAGEA1)
  • Host Species Mammalian Cell
  • Species Reactivity Hu
  • Target Name MAGEA1
  • Alternative Names "Antigen MZ2-E Cancer/testis antigen 1.1 Short name: CT1.1 MAGE-1 antigen"
  • Accession No. Uniprot ID: P43355
  • SDS-PAGE MW 55.19kDa
  • Target Length Full Length,1-309aa
  • Tag Info C-terminal Flag-tagged
  • Target Sequence MSLEQRSLHCKPEEALEAQQEALGLVCVQAATSSSSPLVLGTLEEVPTAGSTDPPQSPQGASAFPTTINFTRQRQPSEGSSSREEEGPSTSCILESLFRAVITKKVADLVGFLLLKYRAREPVTKAEMLESVIKNYKHCFPEIFGKASESLQLVFGIDVKEADPTGHSYVLVTCLGLSYDGLLGDNQIMPKTGFLIIVLVMIAMEGGHAPEEEIWEELSVMEVYDGREHSAYGEPRKLLTQDLVQEKYLEYRQVPDSDPARYEFLWGPRALAETSYVKVLEYVIKVSARVRFFFPSLREAALREEEEGV
  • Formulation Tris-based buffer,50% glycerol
  • Storage "The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃."
Application Details

 

Greater than 90% as determined by SDS-PAGE.

Background

 

May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Regerences

 

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Please let us know if you have published research using #AP74655 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
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