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M-CSF Receptor (Phospho-Tyr809) Conjugated Antibody

C11906
Review: comment rank 5 pdf
  Catalog No. Package Size Price
C11906-AF488 100ul $379.00
C11906-AF594 100ul $379.00
C11906-AF647 100ul $379.00
C11906-AF790 100ul $399.00
C11906-Biotin 100ul $359.00
C11906-Cy3 100ul $379.00
C11906-Cy5 100ul $379.00

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Description
  • Product Name M-CSF Receptor (Phospho-Tyr809) Conjugated Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of M-CSF Receptor only when phosphorylated at tyrosine 809.
  • Immunogen Description Peptide sequence around phosphorylation site of tyrosine 809 (S-N-Y(p)-I-V) derived from Human M-CSF Receptor.
  • Alternative Names CSF1R;C-FMS;CD115;CSFR
  • Accession No. Swiss-Prot#:P07333
    NCBI Gene ID:1436
    NCBI mRNA#:NM_001288705.1
    NCBI Protein#:NP_001275634.1
  • Calculated MW 108
  • Concentration
  • Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 10mg/ml Bovine Serum Albumin, 0.05% Sodium Azide
  • Storage Store at 4℃ in dark for 6 months
Application Details

Biotin conjugated: Working with enzyme-conjugated streptavidin ELISA: 1: 200 - 1: 1,000 Western Blot: 1: 200 - 1: 1,000 IHC/ICC: 1: 100 - 1: 500 Flow Cytometry: 1: 50 - 1: 250 IF: 1: 100 - 1: 500 AF488 conjugated: most apllications: 1: 50 - 1: 250 AF594 conjugated: most apllications: 1: 50 - 1: 250 AF647 conjugated: most apllications: 1: 50 - 1: 250 AF790 conjugated: Western blot: 1: 100-1,000 Cy3 conjugated: most apllications: 1: 50 - 1: 250 Cy5 conjugated: most apllications: 1: 50 - 1: 250
desc_detail:Excitation/Emission Alexa Fluor 488 (AF488): 493nm/519nm Alexa Fluor 594 (AF594): 591nm/614nm Alexa Fluor 647 (AF647): 651nm/667nm Alexa Fluor 790 (AF790): 792nm/803nm Cyanine Cy3 (Cy3): 550nm/570nm Cyanine Cy5 (Cy5): 650nm/670nm

Product Description
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Background
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.
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    Protocol
    Browsing historyclear
    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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