Description
- Product NameVimentin Antibody
- Host SpeciesRabbit
- ClonalityPolyclonal
- PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- ApplicationsWB IF
- Species ReactivityHu Ms Rt Mk
- SpecificityThe antibody detects endogenous level of total Vimentin protein.
- Immunogen TypePeptide-KLH
- Immunogen DescriptionPeptide sequence around aa.452~456(G-Q-V-I-N) derived from Human Vimentin.
- Target NameVimentin
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Alternative Names CTRCT30
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Accession No. Swiss-Prot: P08670
NCBI Protein: NP_003371.2
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UniprotP08670
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Gene ID7431;
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SDS-PAGE MW 57kd
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Concentration 1.0mg/ml
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Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
Sommers C.L., Walker-Jones D., Heckford S.E., Worland P., Valverius E., Clark R., McCormick F.,
Cancer Res. 49:4258-4263(1989)
Kang S.-M., Shin M.-J., Kim J.-H., Oh J.-W. Proteomics 5:2227-2237(2005)
Ahmed B.A., Bukhari I.A., Jeffus B.C., Harney J.T., Thyparambil S., Ziu E., Fraer M., Rusch N.J. PLoS ONE 4:E4730-E4730(2009)
Published Papers
Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancerInCancer Biol TherOn2023 Dec 31byYingying Wang?1,?Lu Meng et al..PMID:?37131290, , (2023),
PMID: 37131290
HIV gp120/Tat protein-induced epithelial-mesenchymal transition promotes the progression of cervical lesionsInAIDS Res TherOn2023 Nov 19byPeizhi Wang?#?1?2,?Baojun Yang et al..PMID:?37981694, , (2023),
PMID: 37981694
Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathwayIn J EthnopharmacolOn2023 Sep 15byMeizhu Wu , Siyu Zhang et al..PMID:37100260, , (2023),
PMID: 37100260
A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection StudiesIn Int J NanomedicineOn2023 Sep 13byYun-E Xu , Di-Shu Ao et al..PMID:37727651, , (2023),
PMID: 37727651
View All Published Papers
Ginsenoside Rg3 Suppresses Epithelial-Mesenchymal Transition via Downregulating Notch-Hes1 Signaling in Colon Cancer Cells. In Am J Chin Med on 2021 by Xiao Li, Wei Liu, et al..PMID:33371813, , (2021),
PMID: 33371813
Qingda granule attenuates cardiac fibrosis via suppression of the TGF-β1/Smad2/3 signaling pathway in vitro and in vivo. In Biomed Pharmacother on 2021 May by Xiaoping Chen, Linzi Long, et al..PMID:33556875, , (2021),
PMID: 33556875
Exosomal miR-423-5p targets SUFU to promote cancer growth and metastasis and serves as a novel marker for gastric cancer.In Mol Carcinog. On 2018 Sep by Yang H, Fu H et al..PMID:29749061, , (2018),
PMID: 29749061
Exosomal TRIM3 is a novel marker and therapy target for gastric cancer.In J Exp Clin Cancer Res.On 2018 Jul 21 by Fu H, Yang H et al..PMID:30031392, , (2018),
PMID: 30031392
Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression.In Int J Oncol on 2014 Mar by Hai Zhang, Shanyu Cheng, et al..PMID: 24378923 , , (2016),
PMID: 24378923
Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness.In BMC Cancer on 2015 Oct 24 by Jianguo Xue , Yuan Zhu et al..PMID: 26498753, , (2015),
PMID: 26498753
Baicalein Inhibits Migration and Invasion of Gastric Cancer Cells Through Suppression of the TGF-β Signaling Pathway.In Mol Med Rep on 2014 Oct by Fenglin Chen, Mingkai Zhuang et al..PMID: 25109410 , , (2014),
PMID: 25109410
Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-kB pathway.In PLoS One on 2014 May 13 by Tingting Yang , Xu Zhang et al..PMID:24824968, , (2014),
PMID: 24824968
SALL4, a novel marker for human gastric carcinogenesis and metastasis.In Oncogene on 2014 Nov 27 by L Zhang , Z Xu et al..PMID:24276240, , (2014),
PMID: 24276240
Foxg1 has an essential role in postnatal development of the dentate gyrus. In J Neurosci on 2012 Feb 29 by Chuanxi Tian, Yifan Gong, et al..PMID:22378868, , (2012),
PMID: 22378868
Please let us know if you have published research using #21488 so that we can cite your reference.
