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Smad1/Smad5/Smad8 Antibody

21684
Review: comment rank 5 pdf
  Catalog No. Package Size Price
21684-1 50ul $189.00
21684-2 100ul $279.00

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Description
  • Product Name Smad1/Smad5/Smad8 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Applications WB
  • Species Reactivity Hu Ms Rt
  • Specificity The antibody detects endogenous level of total Smad1, Smad5, Smad8 protein.
  • Immunogen Type Peptide-KLH
  • Immunogen Description Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.
  • Target Name Smad1/Smad5/Smad8
  • Alternative Names Mad-related protein 1, SMAD 1, hSMAD1, Transforming growth factor-beta-signaling protein 1,
  • Concentration 1.0mg/ml
Application Details

Predicted MW: 60kd
Western blotting: 1: 500~1: 1000

Images
  • Smad1/Smad5/Smad8 Antibody - SAB | Signalway Antibody

    Western blot analysis of extracts from 3T3 cells using Smad1/Smad5/Smad8 Antibody #21684.

Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
    Please let us know if you have published research using #21684 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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