• Product NameGAMT antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody detects endogenous level of total GAMT protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fusion protein of human GAMT (NP_000147.1).
• Target NameGAMT
• Alternative Names    GAMT;CCDS2;HEL-S-20;PIG2;TP53I2
• Accession No. Uniprot:Q14353
  GeneID:2593
• UniprotQ14353
• Gene ID2593
• SDS-PAGE MW 29kDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:50 - 1:200

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

• Western blot analysis of extracts of various cell lines, using GAMT antibody.
• Immunohistochemistry of paraffin-embedded human liver using GAMT Rabbit pAb.
• Immunofluorescence analysis of NIH-3T3 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of U-2 OS cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of A549 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of C6 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of Hep G2 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of Hep G2 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of NIH-3T3 cells using GAMT Rabbit pAb.
• Immunofluorescence analysis of A549 cells using GAMT Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting