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Human CD40,TNFRSF5 ELISA Kit

EK5286
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  Catalog No. Package Size Price
EK5286 96T $599.00

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Description
  • Product Name Human CD40,TNFRSF5 ELISA Kit
  • Specificity Human
  • Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
  • Immunogen Type NSO,E21-R193
  • Alternative Names Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD40; CD40; TNFRSF5;
  • Accession No. P25942
  • Cell Localization Isoform I: Cell membrane; Single-pass type Imembrane protein.
Application Details

sensitivity:1pg ml
Detect Range:15.6pg ml-1000pg ml
sample_type:cell culture supernates serum plasma(heparin EDTA) saliva urine and human milk.
capture_antibody:monoclonal antibody from mouse
detection_antibody:polyclonal antibody from goat
gene_name:CD40
protein_name:Tumor necrosis factor receptor superfamily member 5
gene_full_name:Tumor necrosis factor receptor superfamily member 5
tissue_specificity: B-cells and in primary carcinomas.
sequence_similarities:Contains 4 TNFR-Cys repeats.
tmb_incubation:25-30min
research_category:immunology|adaptive immunity|b cells|cd|cardiovascular|atherosclerosis|vascular inflammation|innate and adaptive immunity|stem cells|hematopoietic progenitors|lymphoid|b lymphocytic lineage|myeloid|dendritic cell lineage

Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human CD40
Background
protein_function: Receptor for TNFSF5,CD40LG. Transduces TRAF6- andMAP3K8-mediated signals that activate ERK in macrophages and Bcells, leading to induction of immunoglobulin secretion.
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B-cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells. The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
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      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
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    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
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    • RbRabbit
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