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Human Fetuin A ELISA Kit

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EK5322 96T $599.00

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  • Product Name Human Fetuin A ELISA Kit
  • Specificity Human
  • Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
  • Immunogen Type NSO,A19-V367
  • Alternative Names Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B; AHSG; FETUA; PRO2743;
  • Accession No. P02765
  • Cell Localization Secreted.
Application Details

sensitivity:10pg ml
Detect Range:0.78ng ml-50ng ml
sample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA).
capture_antibody:monoclonal antibody from mouse
detection_antibody:polyclonal antibody from goat
tissue_specificity: Synthesized in liver and selectivelyconcentrated in bone matrix. Secreted in plasma. It is also foundin dentin in much higher quantities than other plasma proteins.
sequence_similarities:Belongs to the fetuin family.
research_category:cardiovascular|blood|serum proteins|neuroscience|neurology process|neurogenesis|metabolism|types of disease|obesity

Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Fetuin A
protein_function: Promotes endocytosis, possesses opsonic properties andinfluences the mineral phase of bone. Shows affinity for calciumand barium ions.
Alpha2-HS glycoprotein(AHSG), also known as fetuin-A, is a plasma protein displaying high-affinity interaction with calcium phosphate, by which ectopic vascular calcification is prevented. The AHSG polymorphism is attributable to the hereditary variation of AHSG and phosphate serum levels, which may affect skeletal development and chronic disorders such as vascular calcification.1Human plasma protein alpha 2-HS-glycoprotein(AHSG) is composed of two polypeptide chains, A and B, encoded by a single mRNA. Southern blot analysis of mouse x human somatic cell hybrids has mapped the AHSG gene to human chromosome 3 in the region 3q21----qter. Using a recombinant plasmid containing a 1,538 bp insert spanning the entire AHSG coding region, AHSG was localized to chromosomal bands 3q27----q29 by in situ hybridization.2
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