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Human CD244,2B4 ELISA Kit

EK5416
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EK5416 96T $599.00

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Description
  • Product Name Human CD244,2B4 ELISA Kit
  • Specificity Human
  • Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
  • Immunogen Type NSO,C22-R221
  • Alternative Names Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; SLAM family member 4; SLAMF4; Signaling lymphocytic activation molecule 4; CD244; CD244; 2B4;
  • Accession No. Q9BZW8
  • Cell Localization Membrane; Single-pass type Imembrane protein.
Application Details

sensitivity:10pg ml
Detect Range:62.5pg ml-4000pg ml
sample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA).
capture_antibody:monoclonal antibody from mouse
detection_antibody:polyclonal antibody from goat
gene_name:CD244
protein_name:Natural killer cell receptor 2B4
gene_full_name:Natural killer cell receptor 2B4
tissue_specificity: Expressed in spleen PBL followed by lung liver testis and small intestine. Expressed not only in NK cells but also on monocytes and basophils..
sequence_similarities:
tmb_incubation:25-30min
research_category:immunology|cell type markers|cd|nk cells|stem cells|hematopoietic progenitors|lymphoid|t lymphocytic lineage|nk cell lineage

Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human CD244,2B4
Background
protein_function: Modulate other receptor-ligand interactions to enhanceleukocyte activation. CD244,2B4 is the only heterophilic receptorof SLAM family..
CD244(Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. Members of the CD2 family adhere to each other instead,the cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function. The 2B4 gene was mapped to 1q22 on gene map, where SLAM, CD48, CD84 and LY9 are also located. Using recombinant human NK cell-activating ligand 2B4 fused to domains 3 and 4 of rodent Cd4 and flow cytometric analysis, It was found that CD48 binds to 2B4. BIAcore surface plasmon resonance analysis showed that the affinity of CD48 for 2B4 is approximately 10-fold higher than that shown for CD48 and CD2.
    Please let us know if you have published research using #EK5416 so that we can cite your reference.
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
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    • PPig
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