• Product NameMouse GDF-15 ELISA Kit
• SpecificityMouse
• Crossing ReactivityThere is no detectable cross-reactivity with other relevant proteins.
• Immunogen TypeNSO,S189-A303
• Alternative Names    Growth,differentiation factor 15; GDF-15; Gdf15; Sbf;
• Accession No. Q9Z0J7
• UniprotQ9Z0J7
• Gene ID23886;
• Cell Localization Secreted.

• sensitivity:10pg ml
  Detect Range:15.6pg ml-1000pg ml
  sample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA).
  capture_antibody:monoclonal antibody from rat
  detection_antibody:polyclonal antibody from goat
  gene_name:GDF15
  protein_name:Growth differentiation factor 15
  gene_full_name:Growth differentiation factor 15
  tissue_specificity: Highly expressed in liver..
  sequence_similarities:
  tmb_incubation:25-30min
  research_category:cell biology|cell cycle|cell division|cytokinesis|signal transduction|growth factors/hormones|tgf|cytoskeleton / ecm|extracellular matrix|structures|bone|cardiovascular|heart|hypertrophy

• Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse GDF-15

protein_function:
GDF-15(Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an antiinflammatory cytokine by directly interfering with chemokine signaling and integrin activation.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting