protein_function: Functions as transport protein in the blood stream.Binds various ligands in the interior of its beta-barrel domain.Also binds synthetic drugs and influences their distribution andavailability in the body. Appears to function in modulating theactivity of the immune system during the acute-phase reaction..
Alpha-1-acid glycoprotein, or orosomucoid, is a relatively abundant plasma protein synthesized in the liver. It has a molecular weith of 40,000 Da and is a single polypeptide chain of about 180 amino acids. AGP is considered an acute phase reactant; its plasma levels increase several fold during acute infections. It belongs to the lipocalin family and binds numerous basic and neutral lipophilic drugs and steroid hormones. And this gene is located in 9q34.3-qter.