• Product NameBenicar
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityOlmesartan is an antihypertensive agent, which belongs to the class of medications called angiotensin II receptor blockers. It is indicated for the treatment of high blood pressure and is marketed under the name Olmetec?. The FDA label includes a black-box warning of injury and death to the fetus, so women of child-bearing age need to be warned and take the necessary precautions. Olmesartan is also contraindicated in diabetes mellitus patients taking aliskiren.
• Target NameRAAS inhibitor
• CAS No. 144689-63-4
• Calculated MW 558.59
• Formulation C29H30N6O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCCC1=NC(=C(N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)C(=O)OCC1=C(C)OC(=O)O1)C(C)(C)O
  Pathways:Endocrinology/Hormones
  Receptor:angiotensin II receptor
  Boling pt:804.2C?
  Melting pt:180C
  Solubility:DMSO: 89 mg/mL (159.32 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Koike H, et al. J Hypertens Suppl. 2001 Jun;19(1):S3-14.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting