• Product NameHBB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB, IHC
• Species ReactivityHu, Ms, Rt
• SpecificityThe antibody detects endogenous levels of total HBB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human HBB
• Target NameHBB
• Alternative Names    CD113t-C; beta-globin
• Accession No. Swiss-Prot#:P68871
  NCBI Gene ID:3043
  Gene Accssion:NP_000509
• UniprotP68871
• Gene ID3043;
• Calculated MW 16 kDa
• Concentration 0.5
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• WB dilution:1:200-1000
  IHC dilution:1: 10-50

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

• The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47773(HBB Antibody) at dilution 1/20.(Original magnification: 200)
• Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse liver tissue, Human heart tissue and Human plasma solution lysates, Primary antibody:47773(HBB Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting