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Cardiac Troponin /TTNNT2 Antibody

48559
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  Catalog No. Package Size Price
48559-1 50ul $260.00
48559-2 100ul $390.00

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Description
  • Product Name Cardiac Troponin /TTNNT2 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Peptide affinity purified
  • Applications WB, IHC
  • Species Reactivity Hu, Ms, Rt
  • Immunogen Description Synthetic peptide (KLH-coupled) within human TNNT2 1-100 aa.
  • Alternative Names Cardiac muscle troponin T antibody
    Cardiomyopathy dilated 1D (autosomal dominant) antibody
    Cardiomyopathy hypertrophic 2 antibody
    CMD1D antibody
    CMH2 antibody
    CMPD2 antibody
    cTnT antibody
    LVNC6 antibody
    MGC3889 antibody
    OTTHUMP00000033864 antibody
    OTTHUMP00000033865 antibody
    OTTHUMP00000033866 antibody
    OTTHUMP00000033867 antibody
    OTTHUMP00000033870 antibody
    OTTHUMP00000218095 antibody
    RCM3 antibody
    TNNT 2 antibody
    TNNT2 antibody
    TNNT2_HUMAN antibody
    TnTc antibody
    Troponin T cardiac muscle antibody
    Troponin T type 2 (cardiac) antibody
    Troponin T type 2 cardiac antibody
    Troponin T, cardiac muscle antibody
    Troponin T2 cardiac antibody
  • Accession No. Swiss-Prot#:P45379
  • Calculated MW 36 kDa
  • Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage Store at -20˚C
Application Details

WB: 1:5000
IHC: 1:200


Images
  • Cardiac Troponin /TTNNT2 Antibody - SAB | Signalway Antibody

    Western blot analysis of TNNT2 on different lysates using anti-TNNT2 antibody at 1/5,000 dilution.


  • Cardiac Troponin /TTNNT2 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-TNNT2 antibody. Counter stained with hematoxylin.

Background
Troponin T type 2 (cardiac), also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations of this gene may be associated with mild or absent hypertrophy and predominant restrictive disease, with a high risk of sudden cardiac death.
Regerences
1. Gentile A. et al. Human epicardium-derived cells fuse with high efficiency with skeletal myotubes and differentiate toward the skeletal muscle phenotype: a comparison study with stromal and endothelial cells. Mol Biol Cell 22:581-92 (2011).
2. Stefanovic S. et al. Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J Cell Biol 186:665-73 (2009).
    Please let us know if you have published research using #48559 so that we can cite your reference.
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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