• Product NameIP3 Receptor Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JA11-35
• PurificationProA affinity purified
• ApplicationsWB, IHC
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• Alternative Names    4 antibody
  5-trisphosphate receptor antibody
  5-trisphosphate receptor type 1 antibody
  DKFZp313E1334 antibody
  DKFZp313N1434 antibody
  inositol 1 4 5 triphosphate receptor type 1 antibody
  Inositol 1 4 5 trisphosphate Receptor Type 1 antibody
  Inositol 1 antibody
  InsP3R1 antibody
  IP3 antibody
  IP3 receptor antibody
  IP3 receptor isoform 1 antibody
  IP3R 1 antibody
  IP3R antibody
  IP3R1 antibody
  ITPR 1 antibody
  Itpr1 antibody
  ITPR1_HUMAN antibody
  SCA15 antibody
  SCA16 antibody
  SCA29 antibody
  Type 1 inositol 1 4 5 trisphosphate receptor antibody
  Type 1 inositol 1 antibody
  Type 1 InsP3 receptor antibody
  
• Accession No. Swiss-Prot#:Q14643
• UniprotQ14643
• Gene ID3708;
• Calculated MW 314 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500
  IHC: 1:50-1:200
  
  
  

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

• Immunohistochemical analysis of paraffin-embedded mouse hippocampus tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting