• Product NameAtg16L1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JU30-62
• PurificationProA affinity purified
• ApplicationsWB
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• Alternative Names    A16L1_HUMAN antibody
  APG16 like 1 antibody
  APG16-like 1 antibody
  APG16L antibody
  APG16L beta antibody
  ATG16 autophagy related 16 like 1 antibody
  ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody
  ATG16A antibody
  ATG16L antibody
  Atg16l1 antibody
  Autophagy related protein 16 1 antibody
  Autophagy-related protein 16-1 antibody
  FLJ00045 antibody
  FLJ10035 antibody
  FLJ10828 antibody
  FLJ22677 antibody
  IBD10 antibody
  OTTHUMP00000164391 antibody
  OTTHUMP00000164393 antibody
  OTTHUMP00000165876 antibody
  OTTHUMP00000165877 antibody
  WD repeat domain 30 antibody
  WDR30 antibody
  
• Accession No. Swiss-Prot#:Q676U5
• UniprotQ676U5
• Gene ID55054;
• Calculated MW 68/66 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:2,000
  
   

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Plays a role in regulating morphology and function of Paneth cell.

• Western blot analysis of Atg16L1 on Hela and PC-12 cell lysates using anti-Atg16L1 antibody at 1/500 dilution.
• Western blotting analysis using Atg16L1 Antibody #49751.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting