FormulationTris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
StorageStore at 2-8C. Do not freeze.
Recommended working dilution range:1:100 - 1:200
The Her2/Neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between Her2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.
Suthipintawong C, et al. Diagn Cytopathol. 1997; 17:127-33. Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9. Fernndez Ace?ero MJ, et al. Gen Diagn Pathol. 1997; 142:289-96. Koeppen HKW, et al. Histopathology. 2001; 38:96-104. Moch H, et al. Virchows Arch A Pathol Anat Histopathol. 1993; 423:329-34. Cetin B, et al. Transl Gastroenterol Hepatol. 2016; 1:59.