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PDGFRb (Phospho-Tyr771) Conjugated Antibody

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  Catalog No. Package Size Price
C11907-AF350 100ul $399.00
C11907-AF405 100ul $399.00
C11907-AF488 100ul $399.00
C11907-AF555 100ul $399.00
C11907-AF594 100ul $399.00
C11907-AF647 100ul $399.00
C11907-AF680 100ul $399.00
C11907-AF750 100ul $399.00
C11907-Biotin 100ul $399.00

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  • Product Name PDGFRb (Phospho-Tyr771) Conjugated Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Species Reactivity Hu
  • Specificity The antibody detects endogenous level of PDGFRb only when phosphorylated at tyrosine 771.
  • Immunogen Description Peptide sequence around phosphorylation site of tyrosine 771 (S-N-Y(p)-M-A) derived from Human PDGFRb.
  • Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
  • Excitation Emission AF350: 346nm/442nm
    AF405: 401nm/421nm
    AF488: 493nm/519nm
    AF555: 555nm/565nm
    AF594: 591nm/614nm
    AF647: 651nm/667nm
    AF680: 679nm/702nm
    AF750: 749nm/775nm
  • Alternative Names CD140b;PDGF-R-beta;PDGFR;PGFRB;kinase PDGFR-beta
  • Accession No. Swiss-Prot#:P09619
    NCBI Gene ID:5159
    NCBI mRNA#:NM_002609.3
    NCBI Protein#: NP_002600.1
  • Calculated MW 190
  • Concentration
  • Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
  • Storage Store at 4˚Cin dark for 6 months
Application Details

Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Product Description
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
PDGF Receptor β encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
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    • WBWestern Blotting
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    • IFImmunofluorescence
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    • EELISA
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    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
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