• Product NameS100A10 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    42C antibody
  AA409961 antibody
  AL024248 antibody
  Annexin II ligand antibody
  Annexin II ligand, calpactin I, light polypeptide antibody
  Annexin II tetramer (AIIt) p11 subunit antibody
  Annexin II, light chain antibody
  ANX2L antibody
  ANX2LG antibody
  Ca[1] antibody
  CAL12 antibody
  CAL1L antibody
  Calpactin I light chain antibody
  Calpactin I, p11 subunit antibody
  Calpactin-1 light chain antibody
  Cellular ligand of annexin II antibody
  CLP11 antibody
  GP11 antibody
  MGC111133 antibody
  Nerve growth factor-induced protein 42C antibody
  OTTHUMP00000015269 antibody
  OTTHUMP00000015270 antibody
  p10 antibody
  p10 protein antibody
  p11 antibody
  Protein S100 A10 antibody
  Protein S100-A10 antibody
  S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) antibody
  S100 calcium binding protein A10 (calpactin) antibody
  S100 calcium binding protein A10 antibody
  S100 calcium-binding protein A10 antibody
  S100a10 antibody
  S10AA_HUMAN antibody
  
• Accession No. Swiss-Prot#:P60903
  
• UniprotP60903
• Gene ID6281;
• Calculated MW 11 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting