• Product Namealpha 1 Antichymotrypsin Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    SERPINA3 antibody
  AACT antibody
  AACT_HUMAN antibody
  ACT antibody
  Alpha-1-antichymotrypsin His-Pro-less antibody
  Antichymotrypsin antibody
  Cell growth inhibiting gene 24/25 protein antibody
  Cell growth-inhibiting gene 24/25 protein antibody
  GIG24 antibody
  GIG25 antibody
  Growth inhibiting protein 24 antibody
  Growth inhibiting protein 25 antibody
  MGC88254 antibody
  Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3 antibody
  Serine (or cysteine) proteinase inhibitor clade A member 3 antibody
  Serine proteinase inhibitor clade A member 3 antibody
  Serpin A3 antibody
  Serpin family A member 3 antibody
  Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 antibody
  SERPINA3 antibody
  
• Accession No. Swiss-Prot#:P01011
  
• UniprotP01011
• Gene ID12;
• Calculated MW 60 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting