• Product NamePPP6R2 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human PPP6R2 (NP_001229827.1).
• Alternative Names    PPP6R2; KIAA0685; PP6R2; SAP190; SAPS2; protein phosphatase 6 regulatory subunit 2
• Accession No. Swiss-Prot#:O75170
  NCBI Gene ID:9701
• UniprotO75170
• Gene ID9701;
• Calculated MW 105kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment.

• Western blot analysis of extracts of various cell lines, using PPP6R2 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting