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Mouse anti-Human CD80, APC Conjugated mAb

28297
Review: comment rank 5 pdf
  Catalog No. Package Size Price
28297-1 25 Tests $219.00
28297-2 100 Tests $499.00

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Description
  • Product Name Mouse anti-Human CD80, APC Conjugated mAb
  • Clone No. 4AGHI/61
  • Isotype IgG1, k
  • Applications FC
  • Species Reactivity Human, Not yet tested in other species.
  • Storage Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Application Details

Format: APC

Vol.per.Test: 20 μl to 5 μl per test

Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Product Description

Mouse Monoclonal Antibody

Background

CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. 

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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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