Your Position: Home > Recombinant Proteins > Recombinant 2019-nCoV S Protein RBD-SD1 (C-mFC)

Recombinant 2019-nCoV S Protein RBD-SD1 (C-mFC)

Review: comment rank 5 pdf
  Catalog No. Package Size Price
AP89514-1 50ug $354.00
AP89514-2 500ug $2667.00
AP89514-3 1mg $4000.00

Availability: promotionYes

add promotion
  • Product Name Recombinant 2019-nCoV S Protein RBD-SD1 (C-mFC)
  • Brief Description Recombinant Proteins
  • Purification Greater than 95% as determined by reducing SDS-PAGE.
  • Biological Activity Immobilized Human ACE-2-Fc at 10μg/ml (100 μl/well) can bind 2019-nCoV S Protein RBD-SD1-mFc. The ED50 of 2019-nCoV S Protein RBD-SD1-mFc is 15.5 ng/ml.
  • Alternative Names 2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
  • Accession No. Uniprot ID: QHD43416.1
  • Calculated MW 57kDa
  • Storage Reconstituted protein solution should be stored at <-20˚C.
Application Details

Expression Region: Recombinant 2019-nCoV S protein RBD Protein is produced by our Mammalian expression system and the target gene encoding Arg319-Pro589 is expressed with a mFC tag at the C-terminus.

Relevance: Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Storage Buffer: Supplied as a 0.2 μM filtered solution of PBS, pH 7.4

    Please let us know if you have published research using #AP89514 so that we can cite your reference.
Customer Reviews and Rankings
  • No comment
  • Total 0 results, divided into1 pages. First Prev Next Last

    My Review

    Username: Anonymous user
    Verification code: captcha
    Browsing historyclear
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
    • Inspiration, ideas and your feedback.

    facebook twitter linkedin

    sab © 2019 Signalway Antibody LLC. All Rights Reserved.  E-mail: