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Enzymes

p70 S6 Kinase(Phospho-Ser424) Antibody #11284

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
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Description
  • Product Namep70 S6 Kinase(Phospho-Ser424) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at serine 424.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 424 (P-V-S(p)-P-V) derived from Human p70 S6 Kinase.
  • Target Namep70 S6 Kinase
  • ModificationPhospho
  • Alternative Names    KS6B1; P70-S6K; RPS6KB1; S6K;
  • Accession No. Swiss-Prot: P23443
    NCBI Protein: NP_003152.1
  • UniprotP23443
  • Gene ID6198;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Inhibition of mTOR signaling protects photoreceptor cells against serum deprivation by reducing oxidative stress and inducing G2/M cell cycle arrest.In Mol Med Rep on 2016 May by Bin Fan , Fu-Qaing Li et al..PMID: 27035647, , (2016),
PMID: 27035647
Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma?.In Cancer on 2011 Aug 15 by Dan Liu, Yi Huang, et al..PMID:21387259, , (2011),
PMID: 21387259
Dauricine Inhibits Insulin-Like Growth factor-I-induced Hypoxia Inducible Factor 1alpha Protein Accumulation and Vascular Endothelial Growth Factor Expression in Human Breast Cancer Cells.In Acta Pharmacol Sin on 2009 May by Xu-dong Tang , Xin Zhou,et al..PMID:19349962, , (2009),
PMID: 19349962
Please let us know if you have published research using #11284 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep