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Enzymes

CaMKII(Phospho-Thr286) Antibody #11287

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Catalog No. Package Size Price Quantity
50ul $339.00
100ul $529.00
Availability:Yes
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Description
  • Product NameCaMKII(Phospho-Thr286) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of CaMKII only when phosphorylated at threonine 286.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 286 (Q-E-T(p)-V-D) derived from Human CaMKII.
  • Target NameCaMKII
  • ModificationPhospho
  • Alternative Names    CAMKA
  • Accession No. Swiss-Prot: Q9UQM7
    NCBI Protein: NP_057065.2
  • UniprotQ9UQM7
  • Gene ID815;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Roles of transient receptor potential channel 6 in glucose-induced cardiomyocyte injury. In World J Diabetes on 2022 Apr 15 by Shi-Jun Jiang,et al..PMID:35582666, , (2022),
PMID: 35582666
Cardiotoxicity of sorafenib is mediated through elevation of ROS level and CaMKII activity and dysregulation of calcium homoeostasis.In Basic Clin Pharmacol Toxicol on 2020 Feb; by Ma W, Liu M, et al..PMID:31483925, , (2020),
PMID: 31483925
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway.In Br J Pharmacol on 2015 Dec by Xing-Zhu Lu, Xue-Yuan Bi et al..PMID: 25953628, , (2015),
PMID: 25953628
Mechanisms underlying a decrease in KCl-induced contraction after long-term serum-free organ culture of rat isolated mesenteric artery.In J Vet Med Sci on 2014 Jul by Tomoka Morita, Muneyoshi Okada et al..PMID: 24694942, , (2014),
PMID: 24694942
View All Published Papers HIV subtypes B and C gp120 and methamphetamine interaction: dopaminergic system implicates differential neuronal toxicity.In Sci Rep on 2015 Jun 9 by Thangavel Samikkannu, Kurapati V K Rao et al..PMID: 26057350, , (2014),
PMID: 26057350
Please let us know if you have published research using #11287 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep