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Enzymes

TrkB(Phospho-Tyr515) Antibody #11327

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameTrkB(Phospho-Tyr515) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsIF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 515.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y(p)-F-G) derived from Human TrkB.
  • Target NameTrkB
  • ModificationPhospho
  • Alternative Names    BDNF/NT-3 growth factors receptor precursor; GP145-TrkB; GP145-TrkB/GP95-TrkB; NTRK2; Trk-B
  • Accession No. Swiss-Prot: Q16620
    NCBI Protein: NP_001007098.1
  • UniprotQ16620
  • Gene ID4915;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Sex-specific and region-specific changes in BDNF�CTrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice. In Brain Res on 2012 May 3 by YeeWen Candace Wu, Rachel A Hill, et al..PMID:22464183, , (2012),
PMID: 22464183
The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.In Acta Pharmacol Sin on 2010 Mar by Li N, Liu GT et al..PMID:20154710, , (2010),
PMID: 20154710
Please let us know if you have published research using #11327 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep