• Product NameSYTL5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA,WB,IHC-P
• Species ReactivityHu Ms Rt
• SpecificityMultiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 17 amino acid peptide near the amino terminus of human SYTL5.
• Target NameSYTL5
• Alternative Names    SLP5, Synaptotagmin-like protein 5
• Accession No. Swiss-Prot:Q8TDW5
  Gene ID:94122
• UniprotQ8TDW5
• Gene ID94122;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.

• Western blot analysis of SYTL5 in Hela cell lysate with SYTL5 antibody at (A) 1 and (B) 2 ug/mL .
• Immunohistochemistry of SYTL5 in rat liver tissue with SYTL5 antibody at 5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting