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IGF-1R(Ab-1165/1166) Antibody #21081

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameIGF-1R(Ab-1165/1166) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of total IGF-1R protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.1163~1167/1164~1168 (T-D-Y-Y-R-K) derived from Human IGF-1R .
  • Target NameIGF-1R
  • Alternative Names    Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
  • Accession No. Swiss-Prot: P08069
    NCBI Protein: NP_000866.1
  • UniprotP08069
  • Gene ID3480;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

PristimerIn attenuates cell proliferation of uveal melanoma cells by InhibitIng InsulIn-like growth factor-1 receptor and its downstream pathways. In J Cell Mol Med on 2019 Nov by Xie X, Xie S, et al..PMID:31508890, , (2019),
PMID: 31508890
Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways.In Int J Mol Sci. On 2018 Sep 12 by Wang H, Su X et al..PMID: 30213025, , (2018),
PMID: 30213025
H 2 O 2 Attenuates IGF-1R Tyrosine Phosphorylation and Its Survival Signaling Properties in Neuronal Cells via NR2B Containing NMDA Receptor.In Oncotarget on 2017 Jun 27 by Zhiwen Zeng, Dejun Wang,et al..PMID: 29029433, , (2017),
PMID: 29029433
The effects of induced type-I diabetes on developmental regulation of insulin & insulin like growth factor-1 (IGF-1) receptors in the cerebellum of rat neonates.In Metab Brain Dis on 2013 Sep by Haghir H, Rezaee AA, et al..PMID:23397157, , (2013),
PMID: 23397157
View All Published Papers Glutamate Attenuates IGF-1 Receptor Tyrosine Phosphorylation in Mouse Brain: Possible Significance in Ischemic Brain Damage.In Neurosci Res on 2012 Dec by Chengming Sun, Qian Meng,et al..PMID:23085572, , (2012),
PMID: 23085572
Please let us know if you have published research using #21081 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep