• Product NameTNF Receptor I Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB 
• Species ReactivityHu Ms Rt  
• Immunogen DescriptionKLH conjugated synthetic peptide aa 22-72 455 derived from human TNF Receptor I
• ConjugatesHRP
• Excitation EmissionN A
• Target NameTNFR1
• Alternative Names    Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; TNFRSF1A; TNFAR; TNFR1
• Accession No. Swiss-Prot#P19438
  NCBI Gene ID7132
• UniprotP19438
• Gene ID7132;
• Cell Localization Extracellular, Cell membrane
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000  

Receptor for TNFSF2 TNF-alpha and homotrimeric TNFSF1 lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting