• Product NameTRPC6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• SpecificityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionA synthetic peptide of human TRPC6 (NP_004612.2).
• Target NameTRPC6
• Alternative Names    TRPC6;FSGS2;TRP6
• Accession No. Uniprot:Q9Y210
  GeneID:7225
• UniprotQ9Y210
• Gene ID7225
• SDS-PAGE MW 106KDa
• Concentration 1.0mg/ml
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

• Western blot analysis of extracts of Mouse pancreas, using TRPC6 antibody.
• Western blot analysis of extracts of Rat brain, using TRPC6 antibody.
• Immunohistochemistry of paraffin-embedded mouse kidney using TRPC6 Rabbit pAb.
• Immunohistochemistry of paraffin-embedded human esophageal cancer using TRPC6 Rabbit pAb.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting