Home
Antibodies
Proteins
IVD Raw Materials
Assay Kits
ELISA Kits
KD/KO Validation
About Us
Enzymes

FAK(Phospho-Tyr397) Antibody #11215

Review:
Datasheet PDF
add to favorites
Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
Total:
ADD TO CART
 
Datasheet Images Protocol
Description
  • Product NameFAK(Phospho-Tyr397) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of FAK only when phosphorylated at Tyrosine 397.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK.
  • Target NameFAK
  • ModificationPhospho
  • Alternative Names    FAK; FAK1; PTK2
  • Accession No. Swiss-Prot: Q05397
    NCBI Protein: NP_001186578.1
  • UniprotQ05397
  • Gene ID5747;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Isobutyric acid promotes colorectal cancer metastasis through activating RACK1 In Cancer Sci On2023 OctbyJinglian Chen , Jiali Tang et al..PMID:37519194, , (2023),
PMID: 37519194
Focal adhesion kinase signaling is necessary for the hydrogen sulfide-enhanced proliferation, migration, and invasion of HTR8/SVneo human trophoblastsInOnby et al..PMID:, , (2023),
PMID:
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cellsIn PLoS OneOn2023 Apr 21byChunyan Xu? ,?Wenlu Zhang et al..PMID:37083591, , (2023),
PMID: 37083591
Focal adhesion kinase signaling is necessary for the hydrogen sulfide-enhanced proliferation, migration and invasion of HTR8/SVneo human trophoblasts, , (2022),
PMID: #N/A
View All Published Papers Anti-cancer effect of orally absorbable heparin on orthotopically induced exocrine and endocrine pancreatic cancer. In Cancers (Basel) on 2021 Nov 18 by Hae Hyun Hwang, Hee Jeong Jeong, et al..PMID:34830928 , , (2021),
PMID: 34830928
PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.In Cell Death Dis.On 2018 May 1 by PMID: 29752441 , , (2018),
PMID: 29752441
Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells.In Cancer Sci on 2017 Dec by Reiko Satow , Shota Inagaki,et al..PMID: 29024195, , (2017),
PMID: 29024195
Inhibition of hypoxia-induced epithelial mesenchymal transition by luteolin in non-small cell lung cancer cells. In Mol Med Rep on 2012 Jul by Junshan Ruan, Lei Zhang, et al..PMID: 22552526, , (2012),
PMID: 22552526
Luteolin reduces the invasive potential of malignant melanoma cells by targeting β3 integrin and the epithelial-mesenchymal transition.In Acta Pharmacol Sin on 2012 Oct by Ruan JS, Liu YP,et al..PMID:22983392, , (2012),
PMID: 22983392
Please let us know if you have published research using #11215 so that we can cite your reference.

Customer Reviews and Rankings

No comment
Total 0 results, divided into1 pages. First Prev Next Last

My Review

Username:Anonymous user
E-mail:
Ratings:
Content:
Verification code:captcha

Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep