• Product NameALS2CR8 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ALS2CR8 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ALS2CR8.
• Target NameALS2CR8
• Alternative Names    Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; Testis development protein NYD-SP24;
• Accession No. Swiss-Prot: Q8N187
  NCBI Gene ID: 79800
• UniprotQ8N187
• Gene ID79800;
• SDS-PAGE MW 85kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.

Hadano S., Nat. Genet. 29:166-173(2001).
Tao X., Neuron 33:383-395(2002).
Hillier L.W., Nature 434:724-731(2005)

• Western blot analysis of extracts from HuvEc cells, using ALS2CR8 antibody #34418.
• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ALS2CR8 antibody #34418.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting