• Product NameCRABP2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• ApplicationsWB
• Species ReactivityHu Rt
• SpecificityThe antibody detects endogenous levels of total CRABP2 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2
• Target NameCRABP2
• Alternative Names    RBP6; CRABP-II;
• Accession No. Swiss-Prot: P29373
  NCBI Protein: NP_001186652.1
• UniprotP29373
• Gene ID1382;
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

• Predicted MW: 16kd
  Western blotting: 1:500~1:1000
   

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors "Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest."

Budhu A.S., Noy N. Mol. Cell. Biol. 22:2632-2641(2002) "A ligand-activated nuclear localization signal in cellular retinoic acid binding protein-II."
Sessler R.J., Noy N. Mol. Cell 18:343-353(2005)

• Western blot analysis of extracts from MCF-7 and HT-29 cells using CRABP2 Antibody #21647.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting