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EID1 Antibody

36436
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  Catalog No. Package Size Price
36436 100ul $279.00

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Description
  • Product Name EID1 Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications IHC
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous levels of total EID1 protein.
  • Immunogen Type Recombinant Protein
  • Immunogen Description Fusion protein corresponding to residues near the N terminal of human EP300 interacting inhibitor of differentiation 1
  • Target Name EID1
  • Alternative Names CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620
  • Accession No. Swiss-Prot#: Q9Y6B2
    NCBI Gene ID: 23741
    Gene Accssion: NP_055150
  • Concentration 0.7mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Immunohistochemistry: 1:25-1:100

Images
  • EID1 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #36436 at dilution 1/20.

  • EID1 Antibody - SAB | Signalway Antibody

    Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36436 at dilution 1/20.

Background
E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
    Please let us know if you have published research using #36436 so that we can cite your reference.
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    Protocol
    Browsing historyclear
    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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