Product Detail
Product NameStat3 (phospho-Ser754) rabbit pAb
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse
SpecificityThis antibody detects endogenous levels of Human Mouse Stat3 (phospho-Ser754)
Immunogen DescSynthesized phosho peptide around human Stat3 (Ser754)
ConjugateUnconjugated
Other NamesSignal transducer and activator of transcription 3 (Acute-phase response factor)
Accession NoSwiss Prot:P40763
GeneID:6774
Uniprot
P40763
Gene ID
6774
Sdspage MW88
Concentration1 mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage-20˚C/1
Application Details
WB 1:1000-2000
signal transducer and activator of transcription 3(STAT3) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper
If you have published an article using product 13504, please notify us so that we can cite your literature.
et al,AHR Agonist ITE Boosted PD1 Antibody’s Effects by Inhibiting Myeloid-Derived Cells Suppressive Cells in an Orthotopic Mouse Glioma Model
, (2025),
PMID:
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