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Location： Home > Polyclonal Antibodies > MAP2 Antibody

MAP2 Antibody#21636

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Product Detail

Product NameMAP2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB IF

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total MAP2 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.1819~1823 (T-A-A-L-A) derived from Human MAP2.

Target NameMAP2

ConjugateUnconjugated

Other NamesMAP2A; MAP2B; MAP2C

Accession NoSwiss-Prot: P11137
NCBI Protein: NP_002365.3

Uniprot P11137

Gene ID 4133;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 55-75(2c/2d), 280(2a/2b)kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200

Western blot analysis of extract from C6 cells using MAP2 Antibody #21636
Immunofluorescence staining of paraffin-embedded Glioma cells of Spinal Cord using MAP2 Antibody #21636.

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

DeGiorgis J.A., Jaffe H., Moreira J.E., Carlotti C.G. Jr. Proteome Res. 4:306-315(2005)
Olsen J.V., Blagoev B., Gnad F., Macek B. Mann M.Cell 127:635-648(2006)
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. Science 316:1160-1166(2007)

If you have published an article using product 21636, please notify us so that we can cite your literature.

et al,Low-intensity pulsed ultrasound improves osseointegration of dental implant in mice by inducing local neuronal production of αCGRP.In Arch Oral Biol on 2020 Apr 28 by Jiang Y, Yuan Y,et al..PMID:32371135 , (2020),
PMID: 32371135
et al,Proteomics and functional study reveal kallikrein-6 enhances communicating hydrocephalus. In Clin Proteomics on 2021 Dec 16 by Lei Yuan, Dongdong Zou,et al..PMID:34915845 , (2021),
PMID: 34915845
et al,Lead exposure represses mitochondrial metabolism by activation of heme-binding protein BACH1 in differentiated SH-SY5Y cell. In Sci Total Environ on 2022 Dec 20 by Xiaoyi Li, Xintong Li,et al..PMID:36096218 , (2022),
PMID: 36096218
et al,Analysis of the expression and distribution of protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 in the normal adult mouse brain.. In Front Neuroanat on 2023 Jan 6 by Hanxiao Jiang, Yuxue Feng, et al..PMID: 36686576 , (2022),
PMID: 36686576
et al,Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2InInflamm RegenOn 2023 Jun 20byZi-Yuan Zhang, Zhao-Yang Zuo et al..PMID:37340465 , (2023),
PMID: 37340465
et al,Neuronal TRPV1-CGRP axis regulates peripheral nerve regeneration through ERK/HIF-1 signaling pathway. , (2025),
PMID: 39792906

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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