Product Detail
Product NameDVL2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total DVL2 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human dishevelled segment polarity protein 2
Target NameDVL2
ConjugateUnconjugated
Other NamesDishevelled-2; DSH homolog 2; DVL2;
Accession NoSwiss-Prot#: O14641
NCBI Gene ID: 1856
Gene Accssion: NP_004413
Uniprot
O14641
Gene ID
1856;
Concentration2.1mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36830 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #36830 at dilution 1/20.
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
If you have published an article using product 36830, please notify us so that we can cite your literature.
et al,Eurycomalactone switched hepatocellular carcinoma cells into quiescence through 5'tRFAla/DVL/β-catenin pathway inhibition.
, (2025),
PMID:
40128187
Yes
