Product Detail
Product NameABCG1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB IHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total ABCG1 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family G (WHITE), member 1
Target NameABCG1
ConjugateUnconjugated
Other NamesABC8; WHITE1
Accession NoSwiss-Prot#: P45844
NCBI Gene ID: 9619
Gene Accssion: NP_004906
Uniprot
P45844
Gene ID
9619;
Sdspage MW76kd
Concentration1.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lysate: 40ug HT-29 cell
Primary antibody: 1/500 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37074 at dilution 1/40.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
If you have published an article using product 37074, please notify us so that we can cite your literature.
et al,Niacin-induced lysosomal free cholesterol efflux via LXRα-mediated signaling pathways in macrophages retards the progression of atherosclerosis
, (2025),
PMID:
Yes
