Product Detail
Product NameCES4A Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total CES4A protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human CES4A
Target NameCES4A
ConjugateUnconjugated
Other NamesCES6; CES8
Accession NoSwiss-Prot#: Q5XG92
NCBI Gene ID: 283848
Uniprot
Q5XG92
Gene ID
283848;
Concentration0.5mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CES4A Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined.
If you have published an article using product 43923, please notify us so that we can cite your literature.
et al,Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway.
, (2025),
PMID:
39912257
The lead time is currently 1 week.
