Product Detail
Product NameSLC8A1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsIHC
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous levels of total SLC8A1 protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human SLC8A1
Target NameSLC8A1
ConjugateUnconjugated
Other NamesNCX1
Accession NoSwiss-Prot#: P32418
NCBI Gene ID: 6546
Uniprot
P32418
Gene ID
6546;
Concentration1mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using SLC8A1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using SLC8A1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
If you have published an article using product 43934, please notify us so that we can cite your literature.
et al,Identification and study of mood-related biomarkers and potential molecular mechanisms in type 2 diabetes mellitus.
, (2025),
PMID:
39915429
The lead time is currently 1 week.
