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ITPA Rabbit mAb#52368

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Product Detail

Product NameITPA Rabbit mAb

Clone No.S01-4D4

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity Purified

ApplicationsWB IHC

Species ReactivityHuman

Immunogen DescA synthetic peptide of human Inosine triphosphate pyrophosphatase

ConjugateUnconjugated

Other NamesMy049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P

Accession NoSwiss-Prot:Q9BY32
GeneID:3704

Uniprot Q9BY32

Gene ID 3704

Calculated MWCalculated MW: 22 kDa; Observed MW: 22 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/1000-1/5000; IHC: 1/20-1/50
Western blot detection of ITPA in Hela cell lysates using ITPA Rabbit mAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.
Immunohistochemistry of Inosine triphosphate pyrophosphatase in paraffin-embedded Human breast cancer tissue using Inosine triphosphate pyrophosphatase Rabbit mAb at dilution 1/50
Swiss-Prot Acc.Q9BY32.Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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