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Location： Home > Polyclonal Antibodies > LILRB4 Rabbit Polyclonal Antibody

LILRB4 Rabbit Polyclonal Antibody#55107

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Product Detail

Product NameLILRB4 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human LILRB4 (NP_001265355.2).

ConjugateUnconjugated

Other NamesLILRB4;CD85K;ILT-3;ILT3;LIR-5;LIR5

Accession NoSwiss Prot:Q8NHJ6
Gene ID:11006

Uniprot Q8NHJ6

Gene ID 11006

Calculated MW49kDa

Sdspage MW49KDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using LILRB4 antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using LILRB4 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human colon carcinoma using LILRB4 Rabbit pAb.
Immunofluorescence analysis of mouse spleen using LILRB4 Rabbit pAb.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

If you have published an article using product 55107, please notify us so that we can cite your literature.

et al,Spatial transcriptomics reveals prognostically LYZ+ fibroblasts and colocalization with FN1+ macrophages in diffuse large B-cell lymphoma. , (2025),
PMID: 39998673

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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