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SB203580

S1764
Review: comment rank 5 pdf
  Catalog No. Package Size Price
S1764-1 10mg $57.00
S1764-2 50mg $82.00
S1764-3 100mg $128.00
S1764-4 200mg $229.00

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Description
  • Product Name SB203580
  • Brief Description Inhibitors
  • Purification 99.42%
  • Biological Activity SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM.
  • Target Name p38 MAPK inhibitor
  • CAS No. 152121-47-6
  • Calculated MW 377.43
  • Formulation C21H16FN3OS
  • Storage 3 years -20˚C powder;2 years -80˚C in solvent;
Images
  • SB203580 - SAB | Signalway Antibody


Product Description

Research Area:Other
SMILES:CS(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1
Pathways:MAPK
Receptor:p38 MAPK
Boling pt:
Melting pt:
Solubility:DMSO: 43 mg/mL (113.92 mM)
Appearance:YellowPowder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

Regerences

1.Ferdinand V. Lali, et al. J Biol Chem, 2000, 275(10), 7395-402.

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