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Enzymes

HDAC5(Phospho-Ser498) Antibody #11193

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameHDAC5(Phospho-Ser498) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms
  • SpecificityThe antibody detects endogenous level of HDAC5 only when phosphorylated at serine498.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of serine 498 (T-Q-S(p)-S-P) derived from Human HDAC5/7.
  • Target NameHDAC5
  • ModificationPhospho
  • Alternative Names    HD5
  • Accession No. Swiss-Prot: Q9UQL6
    NCBI Protein: NP_001015053.1
  • UniprotQ9UQL6
  • Gene ID10014;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

DopamIne receptor antagonists as potential therapeutic agents for ADPKD. In PLoS One on 2019 May 6 by Paul P, Ramachandran S,et al.. PMID:31059522, , (2019),
PMID: 31059522
Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts. In Development on 2010 Apr by Sheng Xia, Xiaogang Li, et al..PMID: 20181743 , , (2010),
PMID: 20181743
Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS.In Blood on 2010 Apr 8 by Weiye Wang, Chang Hoon Ha,et al..PMID:20042720, , (2010),
PMID: 20042720
Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS.In Blood on 2010 Apr 8 by Weiye Wang, Chang Hoon Ha,et al..PMID:20042720, , (2010),
PMID: 20042720
View All Published Papers Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts. In Development on 2010 Apr by Sheng Xia, Xiaogang Li, et al..PMID: 20181743 , , (2010),
PMID: 20181743
GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells., , (2008),
PMID: 18292392
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. , , (2008),
PMID: 18218981
Please let us know if you have published research using #11193 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep