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Enzymes

PKR(Phospho-Thr446) Antibody #11280

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NamePKR(Phospho-Thr446) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous level of PKR only when phosphorylated at threonine 446.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S) derived from Human PKR.
  • Target NamePKR
  • ModificationPhospho
  • Alternative Names    ADRB2; E2AK2; EIF2AK2; EIF2aK; PRKR
  • Accession No. Swiss-Prot: P19525
    NCBI Protein: NP_001129123.1
  • UniprotP19525
  • Gene ID5610;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression.In Int J Neuropsychopharmacol.On 2016 Sep 21 by Du RH, Tan J et al..PMID:27207922, , (2016),
PMID: 27207922
Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues. In Am J Physiol Cell Physiol on 2010 Oct by Suzette Laing, Guohui Wang, et al..PMID: 20554909 , , (2010),
PMID: 20554909
Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues. In Am J Physiol Cell Physiol on 2010 Oct by Suzette Laing, Guohui Wang, et al..PMID: 20554909 , , (2010),
PMID: 20554909
Please let us know if you have published research using #11280 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep