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PKM1 Antibody #21577

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NamePKM1 Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IF
  • Species ReactivityHu Ms
  • SpecificityThe antibody detects endogenous levels of total PKM1 protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa. 399~403(V-R-A-S-S) derived from Human PKM1.
  • Target NamePKM1
  • Alternative Names    PKM; PK3; OIP3; PK2;
  • Accession No. Swiss-Prot: P14618
    NCBI Protein: NP_872270.1
  • UniprotP14618
  • Gene ID5315;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Pyruvate Dehydrogenase A1 Phosphorylated by Insulin Associates with Pyruvate Kinase M2 and Induces LINC00273 through Histone Acetylation. In Biomedicines on 2022 May 27 by Abu Jubayer Hossain, Rokibul Islam, et al..PMID:35740278, , (2022),
PMID: 35740278
Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition. In Biomolecules on 2022 Aug 6 by Seong Ho Kim, Ji Hun Wi, et al..PMID:36008976, , (2022),
PMID: 36008976
A novel miR-206/hnRNPA1/PKM2 axis reshapes the Warburg effect to suppress colon cancer growth. In Biochem Biophys Res Commun on 2020 Oct 22 by Rong Fu, Peng Yang, et al..PMID:32800545, , (2020),
PMID: 32800545
Phosphorylation of pyruvate kinase M2 and lactate dehydrogenase A by fibroblast growth factor receptor 1 in benign and malignant thyroid tissue.In BMC Cancer on 2015 Mar 18 by Paul Kachel , Bogusz Trojanowicz et al..PMID:25880801, , (2015),
PMID: 25880801
View All Published Papers Pyruvate kinase M2 accelerates pro-inflammatory cytokine secretion and cell proliferation induced by lipopolysaccharide in colorectal cancer. In Cell Signal on 2015 Jul by Peng Yang, Zongwei Li, et al..PMID:25778902, , (2015),
PMID: 25778902
Regulatory circuit of PKM2/NF-kB/miR-148a/152-modulated tumor angiogenesis and cancer progression. In Oncogene on 2015 Oct by Q Xu, L-Z Liu,et al..PMID:25703326, , (2015),
PMID: 25703326
PKM2 regulates chromosome segregation and mitosis progression of tumor cells.In Mol Cell on 2014 Jan 9 by Yuhui Jiang, Xinjian Li et al..PMID: 24316223, , (2014),
PMID: 24316223
PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.In Nat Commun on 2014 Nov 21 by Yuhui Jiang , Yugang Wang et al..PMID: 25412762, , (2014),
PMID: 25412762
Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling.In Cell Signal on 2014 Sep by Peng Yang, Zongwei Li et al..PMID:24686087, , (2014),
PMID: 24686087
EGFR-induced and PKCε monoubiquitylation-dependent NF-kB activation upregulates PKM2 expression and promotes tumorigenesis. In Mol Cell on 2012 Dec 14 by Weiwei Yang, Yan Xia, et al..PMID: 23123196, , (2012),
PMID: 23123196
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis. In Cell on 2012 Aug 17 by Weiwei Yang, Yan Xia, et al..PMID: 22901803, , (2012),
PMID: 22901803
Please let us know if you have published research using #21577 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep