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GRIN2B Antibody

37002
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  Catalog No. Package Size Price
37002 100ul $279.00

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Description
  • Product Name GRIN2B Antibody
  • Host Species Rabbit
  • Clonality Polyclonal
  • Purification Antigen affinity purification.
  • Applications WB
  • Species Reactivity Hu Ms
  • Specificity The antibody detects endogenous levels of total GRIN2B protein.
  • Immunogen Type Peptide
  • Immunogen Description Synthetic peptide corresponding to a region derived from internal residues of human glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Target Name GRIN2B
  • Alternative Names MRD6; NR2B; hNR3; GluN2B; NMDAR2B
  • Accession No. Swiss-Prot#: Q13224
    NCBI Gene ID: 2904
    Gene Accssion: NP_000825
  • SDS-PAGE MW 166kd
  • Concentration 1.4mg/ml
  • Formulation Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
  • Storage Store at -20˚C
Application Details

Western blotting: 1:500-1:2000

Images
  • GRIN2B Antibody - SAB | Signalway Antibody

    Gel: 8%SDS-PAGE
    Lysates (from left to right): Mouse brain tissue
    Amount of lysate: 40ug per lane
    Primary antibody: 1/700 dilution
    Secondary antibody dilution: 1/8000
    Exposure time: 40 seconds

Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.?
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    Protocol
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    Note
      Application:
    • WBWestern Blotting
    • IHCImmunohistochemistry
    • IFImmunofluorescence
    • ICCImmunocytochemistry
    • FCFlow Cytometry
    • IPImmunoprecipitation
    • EELISA
    • DBDot Blotting
    • ChIPChromatin Immunoprecipitation
    • GICAGold Immunochromatography Assay
    • NCNegative Control
      Species Reactivity:
    • HuHuman
    • MsMouse 
    • RtRat 
    • Dm Drosophila melanogaster
    • C Caenorhabditis elegans
    • MkMonkey
    • RbRabbit
    • B Bovine 
    • D Dog
    • PPig
    • HmHamster
    • ChHm Chinese Hamster 
    • ChkChicken  
    • ShpSheep  
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